Biochemistry, Pharmacology, Genetics & Chemistry.- The Life Cycle of the Endocannabinoids: Formation and Inactivation.- Endocannabinoid Receptor Pharmacology.- Endocannabinoid Receptors: CNS Localization of the CB1 Cannabinoid Receptor.- Pharmacological Tools in Endocannabinoid Neurobiology.- Genetic Models of the Endocannabinoid System.- Endocannabinoid Signaling in Neural Plasticity.- Lessons from Nonmammalian Species.- Physiology and Pathophysiology.- Roles of the Endocannabinoid System in Learning and Memory.- Endocannabinoids and the Non-Homeostatic Control of Appetite.- Cannabinoid/Endocannabinoid Signaling Impact on Early Pregnancy Events.- Targeting the Cannabinoid System to Produce Analgesia.- Integration of Endocannabinoid Signaling into the Neural Network Regulating Stress-Induced Activation of the Hypothalamic-Pituitary-Adrenal Axis.- Pathology.- Drug Addiction.- Role of Endocannabinoid Signaling in Anxiety and Depression.- Feeding Disorders and Obesity.- Schizophrenia.- Tourette's Syndrome.