Name: Genomic Approaches for Cross-Species Extrapolation in Toxicology (en Inglés)
Price: 697.09 PEN
Availability: InStock
Author: Benson, William H. ; Di Giulio, Richard T.
ISBN: 9781420043341

portada Genomic Approaches for Cross-Species Extrapolation in Toxicology (en Inglés)

Genomic Approaches for Cross-Species Extrapolation in Toxicology (en Inglés)

Formato

Libro Físico

Editorial

CRC Press

Autor

Benson, William H. ; Di Giulio, Richard T.

Año

2006

Idioma

Inglés

N° páginas

216

Encuadernación

Tapa Dura

Dimensiones

23.5 x 16.5 x 1.7 cm

Peso

0.44 kg.

ISBN

142004334x

ISBN13

9781420043341

Categorías

Genética (no médica)
Ciencia, ingeniería y tecnología medioambientales

Genomic Approaches for Cross-Species Extrapolation in Toxicology (en Inglés)

Benson, William H. ; Di Giulio, Richard T. (Autor) · CRC Press · Tapa Dura

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Reseña del libro "Genomic Approaches for Cross-Species Extrapolation in Toxicology (en Inglés)"

The latest tools for investigating stress response in organisms, genomic technologies provide great insight into how different organisms respond to environmental conditions. However, their usefulness needs to be tested, verified, and codified. Genomic Approaches for Cross-Species Extrapolation in Toxicology provides a balanced discussion drawn from the experience of thirty-five scientists and professionals from diverse fields including environmental toxicology and chemistry, biomedical toxicology, molecular biology, genetics, physiology, bioinformatics, computer science, and statistics. The book introduces genomic, transcriptomic, proteomic, and metabolomic technologies. It describes the advantages and challenges associated with these approaches compared to traditional methodologies, particularly from the perspective of cross-species extrapolation within human and environmental toxicology, and explores solutions that will facilitate the incorporation of these technologies into predictive toxicology. The book goes on to identify and prioritize species of animals that can serve as surrogates for environmental and human health in comparative toxicogenomic studies. The chapter authors elucidate similarities and differences among species, relate stressor-mediated responses to adverse outcomes, and extend this science into innovative approaches to risk assessment and regulatory decision-making.