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Biomarkers and genetics in Alzheimer's disease (en Inglés)
Mariem Mhiri
(Autor)
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Our Knowledge Publishing
· Tapa Blanda
Biomarkers and genetics in Alzheimer's disease (en Inglés) - Mhiri, Mariem
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Reseña del libro "Biomarkers and genetics in Alzheimer's disease (en Inglés)"
CSF biomarkers and genetic studies of ApoE make a major contribution to the positive diagnosis of Alzheimer's disease. Our aim was to compare the clinical data, biological and genetic results of the AD population with a group of patients with non-Alzheimer's dementia (D n-MA) and a control population. Methods: This was a retrospective analytical study conducted at the neurology department of the Sahloul University Hospital in Sousse over 3 years (January 2015-December 2017) and included 227 patients meeting the DSM-5 criteria for TNC. The aetiological diagnosis was based on international criteria established through neuropsychological assessment, imaging, CSF biomarker testing and ApoE polymorphism study. Results: The mean age of onset of AD was 70.79 8.93 years. An early age of onset (
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