Name: Cytochrome P450 2d6: Structure, Function, Regulation, and Polymorphism (en Inglés)
Price: 1228.72 PEN
Availability: InStock
Author: Zhou, Shufeng
ISBN: 9781466597877

portada Cytochrome P450 2d6: Structure, Function, Regulation, and Polymorphism (en Inglés)

Cytochrome P450 2d6: Structure, Function, Regulation, and Polymorphism (en Inglés)

Formato

Libro Físico

Autor

Shufeng Zhou

Editorial

CRC Press

Idioma

Inglés

N° páginas

508

Encuadernación

Tapa Dura

Dimensiones

26.7 x 21.3 x 3.3 cm

Peso

1.52 kg.

ISBN13

9781466597877

N° edición

Categorías

Gastroenterología
Farmacología
Biología celular (citología)

Cytochrome P450 2d6: Structure, Function, Regulation, and Polymorphism (en Inglés)

Shufeng Zhou (Autor) · CRC Press · Tapa Dura

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Reseña del libro "Cytochrome P450 2d6: Structure, Function, Regulation, and Polymorphism (en Inglés)"

Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism reviews the current knowledge of CYP2D6 as well as the maturing body of evidence indicating its significance to clinical and pharmacological researchers and practitioners.This book focuses on the critical role CYP2D6 plays in the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural factors of the gene that govern the highly variable metabolism of a number of drugs in clinical use. It highlights the impact of the functional roles of CYP2D6 on clinical practice and drug development and also discusses implications for precise medicine, strategies to avoid adverse drug reactions, and paths for future research.Cytochrome P450 2D6 is a unique, valuable book focusing on a single but immensely powerful human gene. It provides the first single source of comprehensive information on CYP2D6 that serves as an important reference for medical, biomedical, pharmaceutical, and nursing researchers, practitioners, and students.