Name: G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders (en Inglés)
Price: 536.74 PEN
Availability: InStock
Author: Mishra, Ram K. ; Baker, Glen B. ; Boulton, Alan A.
ISBN: 9781489942906

portada G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders (en Inglés)

G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders (en Inglés)

Formato

Libro Físico

Editorial

Humana

Autor

Mishra, Ram K. ; Baker, Glen B. ; Boulton, Alan A.

Idioma

Inglés

N° páginas

433

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 2.3 cm

Peso

0.59 kg.

ISBN13

9781489942906

Categorías

Bioquímica
Biología molecular

G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders (en Inglés)

Mishra, Ram K. ; Baker, Glen B. ; Boulton, Alan A. (Autor) · Humana · Tapa Blanda

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Reseña del libro "G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders (en Inglés)"

The G proteins are a family of structurally homologous, plasma membrane-associated guanine-nucleotide-binding proteins. These proteins play an integral role in the tra- duction of extracellular signals through second messenger systems. As such, G proteins affect a wide variety of intra cellular biochemical reactions by regulating the concent- tion of second messengers in cells. G proteins are heterotrimeric, consisting of a, p, and y polypeptide chains, with G protein specificity largely det- mined by the a-subunit, Molecular cloning of G protein s- units has revealed 23 distinct a-subunits, encoded by 17 different genes. Based on functional measures, G proteins are generally classified into three major categories: the G, family, which is stimulatory for adenylyl cyclase; the G, f- ily, which is inhibitory for adenylyl cyclase; and the G, f- ily, which stimulates phospholipases (Birnbaumer and Birnbaumer, 1995). Alternatively, on the basis of sequence homology, G proteins can be subdivided into four cate- ries: G, G, G, and G12.