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IR Genes: Past, Present, and Future (en Inglés)
Carl W. Pierce
(Autor)
·
Susan E. Cullen
(Autor)
·
Judith A. Kapp
(Autor)
·
Humana
· Tapa Blanda
IR Genes: Past, Present, and Future (en Inglés) - Pierce, Carl W. ; Cullen, Susan E. ; Kapp, Judith A.
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Reseña del libro "IR Genes: Past, Present, and Future (en Inglés)"
The Fifth Ir Gene Workshop was held at the Chase-Park Plaza Hotel, St. Louis, MO, August 28-31, 1982; 240 scientists participated in the Workshop. The man- uscripts compiled in this book describe the state of the art concerning Ir genes. Although the notion of Ir Genes: Past, Present, and Future has not been ad- dressed specifically by each author, the reader is certain to get this flavor from the contributions. In this Preface, we have tried to summarize some of the salient ob- servations and discussions from the Workshop. The mUltiple genes of the I region have been defined traditionally by serolog- ical analysis of intra-H-2 recombinant mice and the pattern of immune responses to certain antigens developed by these recombinant mice. The application of sev- eral new techniques, such as gene cloning and DNA sequencing, production of T and B cell hybridomas, and development of cloned T cell lines has changed this tradition and introduced a new phase into the analysis of the I region, Ia antigens, and Ir genes.