Name: Simultaneous application of CYP inhibitors in AML (en Inglés)
SKU: 65464715
Price: 298.67 PEN
Availability: InStock
Author: Diana Isabella Dmytrow
ISBN: 9786202371360

portada Simultaneous application of CYP inhibitors in AML (en Inglés)

Simultaneous application of CYP inhibitors in AML (en Inglés)

Formato

Libro Físico

Editorial

Our Knowledge Publishing

Autor

Diana Isabella Dmytrow

Año

2025

Idioma

Inglés

N° páginas

108

Encuadernación

Tapa Blanda

Dimensiones

22x15 cm

ISBN13

9786202371360

Simultaneous application of CYP inhibitors in AML (en Inglés)

Diana Isabella Dmytrow (Autor) · Our Knowledge Publishing · Tapa Blanda

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Reseña del libro "Simultaneous application of CYP inhibitors in AML (en Inglés)"

Retrospective case-control study of n = 108 patients with a diagnosis of AML, calculated in advance, during an inpatient stay at a German hospital. Simultaneous CYP inhibitor application was observed in 59 of 108 AML patients (54.6%). 59 AML patients suffered significantly more (p = 0.036) adverse events (1489 out of 2483, 59.9%) than AML patients without simultaneous CYP inhibitor application (994 out of 2483, 40.1%). At least one potential CYP inhibitor interaction was detected in 59 of 59 AML patients who experienced simultaneous CYP inhibitor use. Women had significantly more potential CYP inhibitor interactions per day (0.321) and per hospital stay than men (p=0.038). 721 of the 1,489 adverse events (48.4%) in the n = 59 AML patients corresponded to the side effects of the simultaneously administered CYP inhibitors and were classified as a potential CYP inhibitor interaction. Of n = 108, approximately half of AML patients experienced simultaneous CYP inhibitor administration and suffered at least one potential CYP inhibitor interaction, especially women.