Name: Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)
SKU: 67312771
Price: 235.62 PEN
Availability: InStock
Author: Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi
ISBN: 9780750328081

portada Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Formato

Libro Físico

Editorial

Morgan & Claypool Publishers

Autor

Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi

Año

2015

Idioma

Inglés

N° páginas

114

Encuadernación

Tapa Blanda

Dimensiones

25.4x17.8x0.6 cm

ISBN13

9780750328081

Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)

Mahdi Karimi;Parham Sahandi Zangabad;Amir Ghasemi (Autor) · Morgan & Claypool Publishers · Tapa Blanda

Más barato Libro Nuevo Importado

Envío: 22 a 27 días háb.

S/ 523,60S/ 235,62

-55%

Más rápido Libro Nuevo Importado

Envío: 14 a 19 días háb.

S/ 579,05S/ 260,57

-55%

Costos de importación incluídos en el precio ✅

Libro Nuevo Más barato

Quedan más de 100 unidades

S/ 235,62

Llega entre el 30 Nov y el 10 Dic a CERCADO DE LIMA, Lima. Seleccionar ubicación

Agregar a lista de deseos

Reseña del libro "Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (en Inglés)"

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual- and multi-responsive systems that combine stimuli that could be either internal or external.