Name: Studies on Naturally Occurring and Synthetic Quinones (en Inglés)
SKU: 57564568
Price: 271.13 PEN
Availability: InStock
Author: Pokharna, C. P.
ISBN: 9786202530941

portada Studies on Naturally Occurring and Synthetic Quinones (en Inglés)

Studies on Naturally Occurring and Synthetic Quinones (en Inglés)

Formato

Libro Físico

Autor

C. P. Pokharna

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

192

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x1.1 cm

Peso

0.29 kg.

ISBN13

9786202530941

Categorías

Química

Studies on Naturally Occurring and Synthetic Quinones (en Inglés)

C. P. Pokharna (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Studies on Naturally Occurring and Synthetic Quinones (en Inglés)"

Many synthetic as well as natural products containing the quinone functionality have displayed useful chemotherapeutic activity. Benzoyl/naphthoyl/thienoyl-1,4-benzoquinones have emerged as potential building blocks for the synthesis of medicinally significant anthracyclinones. Anthracyclinones are valuable drugs in the treatment of certain human cancers. The 1,4-benzoquinones are strong electrophiles in the Diels-Alder reactions with variously substituted 1,3-butadienes. This property of quinones has been of great synthetic value.Encouraged by remarkable achievements in the field of naturally occurring as well as synthetic quinones, a systematic study of quinones including their isolation and synthesis have been undertaken. In the present study isolation of quinones from Tecomellaundulata, synthesis of rhinacanthin-A (a naphthoquinone) from lapachol and a number of benzoyl-1,4-benzoquinones were synthesized which are good precursors for the Diels-Alder reaction with various dienes and therefore, this approach may further be extended to the synthesis of anthracyclinones.