Name: Disease and the Hippo Pathway: Cellular and Molecular Mechanisms (en Inglés)
Price: 230.69 PEN
Availability: InStock
Author: Hansen, Carsten Gram
ISBN: 9783039217762

portada Disease and the Hippo Pathway: Cellular and Molecular Mechanisms (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Hansen, Carsten Gram

Idioma

Inglés

N° páginas

226

Encuadernación

Tapa Blanda

Dimensiones

24.4 x 17.0 x 1.5 cm

Peso

0.49 kg.

ISBN13

9783039217762

Categorías

Biología

Disease and the Hippo Pathway: Cellular and Molecular Mechanisms (en Inglés)

Hansen, Carsten Gram (Autor) · Mdpi AG · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Disease and the Hippo Pathway: Cellular and Molecular Mechanisms (en Inglés)"

The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.