Name: Infectious risk in Crohn's disease under immunomodulators (en Inglés)
Price: 257.44 PEN
Availability: InStock
Author: Zaimi, Yosra ; Bel Hadj Mabrouk, Emna ; Mouelhi, Leila
ISBN: 9786205262665

portada Infectious risk in Crohn's disease under immunomodulators (en Inglés)

Formato

Libro Físico

Autor

Yosra Zaimi

Emna Bel Hadj Mabrouk

Leila Mouelhi

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.6 cm

Peso

0.15 kg.

ISBN13

9786205262665

Categorías

Cuestiones generales de la medicina

Infectious risk in Crohn's disease under immunomodulators (en Inglés)

Yosra Zaimi (Autor) · Emna Bel Hadj Mabrouk (Autor) · Leila Mouelhi (Autor) · Our Knowledge Publishing · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Infectious risk in Crohn's disease under immunomodulators (en Inglés)"

Immunomodulators have revolutionized the management of chronic inflammatory bowel disease. Nevertheless, they are associated with an increased risk of opportunistic infections (OIs). The aim of our study was to investigate OIs in Crohn's disease on immunomodulators and to identify associated factors. 77 were included with a M/F sex ratio of 0.75 and a mean age of 45.6 years. A pre-immunomodulator workup was performed in all patients. Antituberculosis chemoprophylaxis was prescribed in 18% of patients. Viral serologies B and C were positive in 8 and 4% of cases. OI occurred in 42 patients with a mean time between treatment with immunomodulators and the occurrence of infection of 3.3 years. OIs were ubiquitous. The infection was bacterial in 71% of cases with a predominance of E.Coli, parasitic in 12% of cases, fungal in 12% of cases and viral in 5% of patients. In a multivariate study, the combination of azathioprine and corticosteroids was the independent predictive factor for the occurrence of OI (p