Name: Roles of clpA and clpB in the virulence of Salmonella Typhimurium (en Inglés)
Price: 241.23 PEN
Availability: InStock
Author: Sangpuii, Lal ; Mahawar, Manish
ISBN: 9786139840809

portada Roles of clpA and clpB in the virulence of Salmonella Typhimurium (en Inglés)

Formato

Libro Físico

Autor

Lal Sangpuii

Manish Mahawar

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

104

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.6 cm

Peso

0.16 kg.

ISBN13

9786139840809

Categorías

Ciencias matemáticas

Roles of clpA and clpB in the virulence of Salmonella Typhimurium (en Inglés)

Lal Sangpuii (Autor) · Manish Mahawar (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

Libro Nuevo

S/ 241,23

S/ 482,45

Ahorras: S/ 241,23

50% descuento

Envío normal

Origen: Estados Unidos (Costos de importación incluídos en el precio)

Se enviará desde nuestra bodega entre el Martes 13 de Agosto y el Martes 27 de Agosto.

Lo recibirás en cualquier lugar de Perú entre 2 y 5 días hábiles luego del envío.

Reseña del libro "Roles of clpA and clpB in the virulence of Salmonella Typhimurium (en Inglés)"

Salmonella Typhimurium encounters several stress, including oxidants generated by the phagocytes and higher (42 C) body temperature inside the poultry host.To withstand such assaults, three types of energy dependant proteases, including the caseinolytic proteases (Clps) family (viz. ClpA, ClpB, ClpX, ClpP), Lon and HslVU are reported in S. Typhimurium. In the current study, comparative roles of two such Clps, clpA (involved in proteolysis) and clpB (involved in protein disaggregation and refolding) in the survival of S. Typhimurium under different stresses and in virulence have been investigated. We deleted clpA and clpB genes (∆clpA and ∆clpB) from S. Typhimurium and then complemented in trans by pQE60 plasmid. ∆clpB strain was comparatively much more susceptible to 42 C, HOCl, paraquat and macrophage than ∆clpA strain. As compared to WT and ∆clpA strains, ∆clpB strain was defective for colonization in the poultry caecum and showed decreased dissemination to spleen and liver. Therefore, ClpB is more important than ClpA for survival of S. Typhimurium under stress and virulence in poultry.